L3MBTL3 antibody (AA 121-200) (AbBy Fluor® 350)
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- Target See all L3MBTL3 Antibodies
- L3MBTL3 (L(3)mbt-Like 3 (L3MBTL3))
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Binding Specificity
- AA 121-200
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This L3MBTL3 antibody is conjugated to AbBy Fluor® 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human L3MBTL3
- Isotype
- IgG
- Top Product
- Discover our top product L3MBTL3 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- L3MBTL3 (L(3)mbt-Like 3 (L3MBTL3))
- Alternative Name
- L3MBTL3 (L3MBTL3 Products)
- Synonyms
- MBT-1 antibody, MBT1 antibody, RP11-73O6.1 antibody, AI481284 antibody, L3MBTL3, histone methyl-lysine binding protein antibody, l(3)mbt-like 3 (Drosophila) antibody, L3MBTL3 antibody, L3mbtl3 antibody
- Background
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Synonyms: Hl3mbt like protein, KIAA1798, l3mbt like 3 Drosophila, l3mbt like 3, L3mbt like 3 protein, Lethal3malignant brain tumor like 3 protein, MBT1, LMBL3_HUMAN.
Background: Polycomb group (PcG) proteins are important for maintaining the transcriptionally repressed state of target genes and are thought to function via chromatin modification. PcG proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. PcG proteins are also required for normal maturation of myeloid progenitor cells. A putative PcG protein, L3MBTL3 (lethal(3)malignant brain tumor-like protein 3), also known as MBT-1 or KIAA1798, is a 780 amino acid protein containing three MBT repeats and one SAM (sterile alpha motif) domain. Localized to the nucleus, L3MBTL3 interacts with RING1B, another PcG protein that may be involved in the specification of anterior-posterior axis and cell proliferation in early development. L3MBTL3 exists as two isoforms produced by alternative splicing events.
- Gene ID
- 84456
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