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G6PC2 antibody (AbBy Fluor® 350)

G6PC2 Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal AbBy Fluor® 350
Catalog No. ABIN1693609
  • Target See all G6PC2 products
    G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))
    Reactivity
    Human, Mouse, Rat
    Host
    • 22
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This G6PC2 antibody is conjugated to AbBy Fluor® 350
    Application
    • 17
    • 7
    • 1
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Cow,Sheep,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase 2/IGRP
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    G6PC2 (Glucose-6-Phosphatase, Catalytic, 2 (G6PC2))
    Alternative Name
    Glucose 6 Phosphatase 2/Igrp (G6PC2 Products)
    Synonyms
    IGRP antibody, G6pc-rs antibody, Igrp antibody, g6pc2 antibody, igrp antibody, glucose-6-phosphatase catalytic subunit 2 antibody, glucose-6-phosphatase, catalytic, 2 antibody, glucose-6-phosphatase, catalytic, 2 S homeolog antibody, G6PC2 antibody, G6pc2 antibody, g6pc2.S antibody
    Background

    Synonyms: G 6 Pase 2, G 6 Pase2, G6Pase 2, G6Pase2, G6PC 2, G6pc rs, G6pcrs, Glucose 6 phosphatase 2, Glucose 6 phosphatase, catalytic, 2, Glucose 6 phosphatase, catalytic, related, Glucose 6 phosphate catalytic 2, Islet specic G6CP related protein, Islet specic glucose 6 phosphatase, Islet specic glucose 6 phosphatase catalytic subunit related protein, G6PC2_HUMAN.

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-alpha, a second form, designated G6Pase-, contributes to blood glucose homeostasis in a wider range of tissues. Islet-specific G-6-Pase catalytic subunit-related protein (IGRP), a homolog of the catalytic subunit of G6Pase, may play a role in the regulation of islet metabolism and in insulin secretion induced by metabolites. The exact catalytic acivity of IGRP is not defined. Identification of inhibitors of IGRP have potential therapeutic benefits for treatment of type 2 diabetes resulting from insulin secretion defects. Structurally, IGRP has been shown to be a glycoprotein held in the endoplasmic reticulum by nine transmembrane domains, which are then degraded in cells through the proteasome pathway generating MHC class I presented peptides.

    Gene ID
    57818
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