ZBTB46 antibody (AbBy Fluor® 350)

Catalog No. ABIN1693209

Product Details anti-ZBTB46 Antibody (AbBy Fluor® 350)

Target: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB46 antibody is conjugated to AbBy Fluor® 350

Application: Western Blotting (WB)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Sheep,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB46/BTBD4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZBTB46

Target: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Alternative Name: Zbtb46/Btbd4 (ZNF340 Products)

Synonyms: btbd4 antibody, rinzf antibody, znf340 antibody, BTBD4 antibody, BZEL antibody, RINZF antibody, ZNF340 antibody, dJ583P15.7 antibody, dJ583P15.8 antibody, 2610019F01Rik antibody, 4933406L05Rik antibody, Btbd4 antibody, zinc finger and BTB domain containing 46 S homeolog antibody, zinc finger and BTB domain containing 46 antibody, zbtb46.S antibody, ZBTB46 antibody, Zbtb46 antibody

Background:

Synonyms: BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing 46, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340, ZBT46_HUMAN.

Background: BTBD4 is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

Gene ID: 140685