PR antibody
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- Target
- PR
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- Un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of PR expressed in E. Coli.
- Clone
- 2F12B4-2F12H2
- Isotype
- IgG1
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- Application Notes
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Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - Restrictions
- For Research Use only
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- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." in: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, (2000) (PubMed).
: "Novel structure and redox chemistry of the prosthetic groups of the iron-sulfur flavoprotein sulfide dehydrogenase from Pyrococcus furiosus; evidence for a [2Fe-2S] cluster with Asp(Cys)3 ligands." in: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, Vol. 5, Issue 4, pp. 527-34, (2000) (PubMed).
: "The A and B isoforms of the human progesterone receptor operate through distinct signaling pathways within target cells." in: Molecular and cellular biology, Vol. 14, Issue 12, pp. 8356-64, (1994) (PubMed).
: "Prognostic factors in primary breast cancer." in: Cancer surveys, Vol. 5, Issue 3, pp. 527-36, (1987) (PubMed).
: "Markets in kidneys." in: Lancet, Vol. 2, Issue 8411, pp. 1102, (1984) (PubMed).
: "
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Safe Motherhood interventions in low-income countries: an economic justification and evidence of cost effectiveness." in: Health policy (Amsterdam, Netherlands), Vol. 53, Issue 3, pp. 201-28, (2000) (PubMed).
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- Target
- PR
- Synonyms
- SPC antibody, proline rich protein gene cluster antibody, PR@ antibody
- Background
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PR(progesterone receptor), with 933-amino acid protein (about 110kDa), a member of the steroid receptor superfamily, mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone.
Synonyms: PR, NR3C3, PGR - Gene ID
- 5241
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