NLRP12 antibody (Internal Region)

Catalog No. ABIN1686781

Product Details anti-NLRP12 Antibody

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Binding Specificity: Internal Region

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This NLRP12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Nalp12 / Nlrp12 (rodent)

Sequence: KPGTPTFKVP ANQR

Cross-Reactivity: Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 100 kDa band observed in Mouse Liver and Spleen lysates (calculated MW of 119 kDa according to NP_001028603.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Jéru et al, Proc Nat

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Alternative Name: Nlrp12 (NLRP12 Products)

Background: Nlrp12, NLR family, pyrin domain containing 12, Nalp12, PYPAF7, NACHT, LRR and PYD containing protein 12, NACHT, LRR and PYD domains-containing protein 12, PYRIN-containing APAF1-like protein 7, monarch-1

Molecular Weight: 100 kDa

Gene ID: 378425, 292541

NCBI Accession: NP_001028603

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome