LRP4 antibody (AA 26-350)

Catalog No. ABIN1686627

Product Details anti-LRP4 Antibody

Target: LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))

Binding Specificity: AA 26-350

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This LRP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: Detects the extracellular domain of LRP4 ~215 kDa. Degradation product can be seen at ~150 kDa.

Cross-Reactivity: Human, Mouse, Rat

Purification: Protein G Purified

Immunogen: Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4

Clone: S207-27

Isotype: IgG2a

Application Details

Application Notes:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Comment:

1 μg/ml of ABIN1686627 was sufficient for detection of LRP4 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C

Target Details for LRP4

Target: LRP4 (Low Density Lipoprotein Receptor-Related Protein 4 (LRP4))

Alternative Name: LRP4 (LRP4 Products)

Synonyms: CLSS antibody, LRP-4 antibody, LRP10 antibody, MEGF7 antibody, SOST2 antibody, Megf7 antibody, 6430526J12Rik antibody, D230026E03 antibody, mdig antibody, LRP4 antibody, lrp10 antibody, megf7 antibody, LDL receptor related protein 4 antibody, low density lipoprotein receptor-related protein 4 antibody, LRP4 antibody, Lrp4 antibody, lrp4 antibody

Background: Potential cell surface endocytic receptor, which binds and internalizes extracellular ligands for degradation by lysosomes. It is involved in the negative regulation of the canonical Wnt signaling pathway, being able to antagonize the LRP6-mediated activation of this pathway.

Gene ID: 83469

NCBI Accession: NP_766256

UniProt: Q8VI56

Pathways: Skeletal Muscle Fiber Development