ARHGEF7 antibody (AA 1-260)

Catalog No. ABIN3021451

Product Details anti-ARHGEF7 Antibody

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Binding Specificity: AA 1-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MNSAEQTVTW LITLGVLESP KKTISDPEGF LQASLKDGVV LCRLLERLLP GTIEKTFDAN DLYQGQNFNK VLSSLVTLNK VTADIGLGSD SVCARPSSHR IKSFDSLGSQ SLHTRTSKLF QGQYRSLDMT DNSNNQLVVR AKFNFQQTNE DELSFSKGDV IHVTRVEEGG WWEGTLNGRT GWFPSNYVRE VKASEKPVSP KSGTLKSPPK GFDTTAINKS YYNVVLQNIL ETENEYSKEL QTVLSTYLRP LQTSEKLSSA

Cross-Reactivity: Human, Monkey, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human ARHGEF7 (NP_001106984.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ARHGEF7

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Alternative Name: ARHGEF7 (ARHGEF7 Products)

Synonyms: BETA-PIX antibody, COOL-1 antibody, COOL1 antibody, Nbla10314 antibody, P50 antibody, P50BP antibody, P85 antibody, P85COOL1 antibody, P85SPR antibody, PAK3 antibody, PIXB antibody, cool1 antibody, p50 antibody, p85 antibody, pak3 antibody, pixb antibody, ARHGEF7 antibody, P85spr antibody, Pak3bp antibody, Cool antibody, PIX antibody, betaPix antibody, betaPix-b antibody, betaPix-c antibody, cool-1 antibody, mKIAA0142 antibody, p85Cool1 antibody, p85SPR antibody, arhgef7 antibody, bbh antibody, bpix antibody, im:7142367 antibody, wu:fc35h08 antibody, zgc:101775 antibody, Rho guanine nucleotide exchange factor 7 antibody, Rho guanine nucleotide exchange factor 7 S homeolog antibody, ankyrin repeat domain 10 antibody, Rho guanine nucleotide exchange factor (GEF7) antibody, Rho guanine nucleotide exchange factor (GEF) 7b antibody, ARHGEF7 antibody, arhgef7.S antibody, arhgef7 antibody, ANKRD10 antibody, Arhgef7 antibody, arhgef7b antibody

Background: This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.,ARHGEF7,BETA-PIX,COOL-1,COOL1,Nbla10314,P50,P50BP,P85,P85COOL1,P85SPR,PAK3,PIXB,Cancer,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Microtubules,Actins,ARHGEF7

Molecular Weight: 70 kDa/73 kDa/82 kDa/84 kDa/87 kDa/90 kDa

Gene ID: 8874

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation