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WISP1 antibody (AA 158-367)

WISP1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1683290
  • Target See all WISP1 Antibodies
    WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
    Binding Specificity
    • 15
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 158-367
    Reactivity
    • 40
    • 26
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 54
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 57
    • 4
    Polyclonal
    Conjugate
    • 26
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WISP1 antibody is un-conjugated
    Application
    • 35
    • 21
    • 20
    • 13
    • 13
    • 8
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    LRVRPPRLWC PHPRRVSIPG HCCEQWVCED DAKRPRKTAP RDTGAFDAVG EVEAWHRNCI AYTSPWSPCS TSCGLGVSTR ISNVNAQCWP EQESRLCNLR PCDVDIHTLI KAGKKCLAVY QPEASMNFTL AGCISTRSYQ PKYCGVCMDN RCCIPYKSKT IDVSFQCPDG LGFSRQVLWI NACFCNLSCR NPNDIFADLE SYPDFSEIAN
    Cross-Reactivity
    Human, Mouse
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 158-367 of human WISP1 (NP_003873.1).
    Isotype
    IgG
    Top Product
    Discover our top product WISP1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    WISP1 (WNT1 Inducible Signaling Pathway Protein 1 (WISP1))
    Alternative Name
    WISP1 (WISP1 Products)
    Synonyms
    CCN4 antibody, WISP1c antibody, WISP1i antibody, WISP1tc antibody, WISP-1 antibody, WISP1 antibody, si:ch211-38f10.2 antibody, AW146261 antibody, Elm1 antibody, zgc:172276 antibody, WNT1 inducible signaling pathway protein 1 antibody, WNT1 inducible signaling pathway protein 1a antibody, WNT1-inducible-signaling pathway protein 1-like antibody, WNT1 inducible signaling pathway protein 1b antibody, WISP1 antibody, wisp1a antibody, Wisp1 antibody, LOC100627044 antibody, wisp1b antibody
    Background
    This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. It is expressed at a high level in fibroblast cells, and overexpressed in colon tumors. The encoded protein binds to decorin and biglycan, two members of a family of small leucine-rich proteoglycans present in the extracellular matrix of connective tissue, and possibly prevents the inhibitory activity of decorin and biglycan in tumor cell proliferation. It also attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase. It is 83 % identical to the mouse protein at the amino acid level. Multiple alternatively spliced transcript variants have been identified.,WISP1,CCN4,WISP1c,WISP1i,WISP1tc,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Stem Cells,WISP1
    Molecular Weight
    13 kDa/16 kDa/21 kDa/30 kDa/40 kDa
    Gene ID
    8840
    UniProt
    O95388
    Pathways
    WNT Signaling, Growth Factor Binding
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