VNN1 antibody (AA 300-415)

Catalog No. ABIN1683272

Product Details anti-VNN1 Antibody

Target: VNN1 (Vanin 1 (VNN1))

Binding Specificity: AA 300-415

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VNN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: LLSQLDSHPS HSAVVNWTSY ASSIEALSSG NKEFKGTVFF DEFTFVKLTG VAGNYTVCQK DLCCHLSYKM SENIPNEVYA LGAFDGLHTV EGRYYLQICT LLKCKTTNLN TCGDSA

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 300-415 of human VNN1 (NP_004657.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VNN1

Target: VNN1 (Vanin 1 (VNN1))

Alternative Name: VNN1 (VNN1 Products)

Synonyms: HDLCQ8 antibody, Tiff66 antibody, V-1 antibody, hdlcq8 antibody, tiff66 antibody, vnn1.1 antibody, vanin-1 antibody, vanin 1 antibody, pantetheinase antibody, VNN1 antibody, Vnn1 antibody, vnn1 antibody, LOC100217969 antibody

Background: This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.,VNN1,HDLCQ8,Tiff66,vanin 1,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Blood,Blood Pressure regulation,VNN1

Molecular Weight: 57 kDa

Gene ID: 8876

UniProt: O95497

Pathways: Negative Regulation of intrinsic apoptotic Signaling