UBC antibody (AA 1-100)

Catalog No. ABIN1683190

Product Details anti-UBC Antibody

Target: UBC (Ubiquitin C (UBC))

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MQIFVKTLTG KTITLEVEPS DTIENVKAKI QDKEGIPPDQ QRLIFAGKQL EDGRTLSDYN IQKESTLHLV LRLRGGMQIF VKTLTGKTIT LEVEPSDTIE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBC (NP_066289.3).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:2000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-UBC antibody (ABIN1683190)

Li, Chan, Yu, Bei, Chen, Zhou, Cheng, Chen, Ziegler, Rowe, Das, Xiao: "miR-29b contributes to multiple types of muscle atrophy." in: Nature communications, Vol. 8, pp. 15201, (2018) (PubMed).

Wang, Hu, Xiao, Wang, Liu, Xu, Shi, Jiang, Huang, Li, Liu, Qing: "Stabilization of Notch1 by the Hsp90 Chaperone Is Crucial for T-Cell Leukemogenesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 14, pp. 3834-3846, (2018) (PubMed).

Xiao, Yue, Su, Ren, Jiang, Li, Hu, Du, Liu, Qing: "Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival." in: Molecular cell, Vol. 64, Issue 3, pp. 493-506, (2017) (PubMed).

Target Details for UBC

Target: UBC (Ubiquitin C (UBC))

Alternative Name: UBC (UBC Products)

Synonyms: HMG20 antibody, 2700054O04Rik antibody, AI194771 antibody, Rps27a antibody, TI-225 antibody, Uba52 antibody, Ubb antibody, ubiquitin C antibody, UBC antibody, Ubc antibody

Background: This gene represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways.,UBC,HMG20,ubiquitin C,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Ubiquitin,Ubiquitin-Proteasome Signaling Pathway,UBC

Molecular Weight: 77 kDa

Gene ID: 7316

UniProt: P0CG48

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, Toll-Like Receptors Cascades, Synthesis of DNA, EGFR Downregulation, Ubiquitin Proteasome Pathway