JUP antibody

Catalog No. ABIN7101634

Product Details anti-JUP Antibody

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human gamma-Catenin

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: JUP (JUP Products)

Background: This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene, however, not all transcripts have been fully described. [provided by RefSeq, Jul 2008],ARVD12, CTNNG, DP3, DPIII, PDGB, PKGB,Cell Adhesion,Cell Adhesion_Tight Junctions,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Signal Transduction,JUP

Molecular Weight: 82 kDa

Gene ID: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location