TCOF1 antibody (AA 659-958)

Catalog No. ABIN1682987

Product Details anti-TCOF1 Antibody

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Binding Specificity: AA 659-958

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCOF1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VRVGTQAPRK AGTATSPAGS SPAVAGGTQR PAEDSSSSEE SDSEEEKTGL AVTVGQAKSV GKGLQVKAAS VPVKGSLGQG TAPVLPGKTG PTVTQVKAEK QEDSESSEEE SDSEEAAASP AQVKTSVKKT QAKANPAAAR APSAKGTISA PGKVVTAAAQ AKQRSPSKVK PPVRNPQNST VLARGPASVP SVGKAVATAA QAQTGPEEDS GSSEEESDSE EEAETLAQVK PSGKTHQIRA ALAPAKESPR KGAAPTPPGK TGPSAAQAGK QDDSGSSSEE SDSDGEAPAA VTSAQDQESS

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 659-958 of human TCOF1 (NP_001008657.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TCOF1

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Alternative Name: TCOF1 (TCOF1 Products)

Synonyms: TCOF1 antibody, AA408847 antibody, AW209012 antibody, treacle antibody, MFD1 antibody, TCS1 antibody, treacle ribosome biogenesis factor 1 antibody, Tcof1 antibody, TCOF1 antibody

Background: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.,TCOF1,MFD1,TCS,TCS1,treacle,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,TCOF1

Molecular Weight: 96 kDa/144 kDa/148 kDa/152 kDa/155 kDa

Gene ID: 6949

UniProt: Q13428