TBX3 antibody (AA 246-385)

Catalog No. ABIN1682975

Product Details anti-TBX3 Antibody

Target: TBX3 (T-Box 3 (TBX3))

Binding Specificity: AA 246-385

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBX3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: HKYQPRFHIV RANDILKLPY STFRTYLFPE TEFIAVTAYQ NDKITQLKID NNPFAKGFRD TGNGRREKRK QLTLQSMRVF DERHKKENGT SDESSSEQAA FNCFAQASSP AASTVGTSNL KDLCPSEGES DAEAESKEEH

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 246-385 of human TBX3 (NP_057653.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TBX3

Target: TBX3 (T-Box 3 (TBX3))

Alternative Name: TBX3 (TBX3 Products)

Background: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.,TBX3,TBX3-ISO,UMS,XHL,T-box 3,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Apoptosis,Cardiovascular,Angiogenesis,TBX3

Molecular Weight: 65 kDa/77 kDa/79 kDa

Gene ID: 6926

UniProt: O15119

Pathways: Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development