TAF9 antibody (AA 1-172)

Catalog No. ABIN1682962

Product Details anti-TAF9 Antibody

Target: TAF9 (RNA Polymerase II TBP-Associated Factor Subunit G (TAF9))

Binding Specificity: AA 1-172

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF9 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLLPNILLTG TPGVGKTTLG KELASKSGLK YINVGDLARE EQLYDGYDEE YDCPILDEDR VVDELDNQMR EGGVIVDYHG CDFFPERWFH IVFVLRTDTN VLYERLETRG YNEKKLTDNI QCEIFQVLYE EATASYKEEI VHQLPSNKPE ELENNVDQIL KWIEQWIKDH NS

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human TAF9 (NP_057367.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TAF9

Target: TAF9 (RNA Polymerase II TBP-Associated Factor Subunit G (TAF9))

Alternative Name: TAF9 (TAF9 Products)

Background: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. In human, TAF9 and AK6 (GeneID: 102157402) are two distinct genes that share 5' exons. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants.,TAF9,MGC:5067,STAF31/32,TAF2G,TAFII-31,TAFII-32,TAFII31,TAFII32,TAFIID32,Epigenetics & Nuclear Signaling,TAF9

Molecular Weight: 28 kDa

Gene ID: 6880

UniProt: Q16594

Pathways: Negative Regulation of intrinsic apoptotic Signaling