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SMC5 antibody (AA 872-1101)

SMC5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1682829
  • Target See all SMC5 Antibodies
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Binding Specificity
    • 15
    • 5
    • 3
    • 1
    • 1
    AA 872-1101
    Reactivity
    • 34
    • 18
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 32
    • 1
    • 1
    Rabbit
    Clonality
    • 34
    Polyclonal
    Conjugate
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMC5 antibody is un-conjugated
    Application
    • 22
    • 13
    • 13
    • 11
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    LTEERSRASC FTGLNPTIVQ EYTKREEEIE QLTEELKGKK VELDQYRENI SQVKERWLNP LKELVEKINE KFSNFFSSMQ CAGEVDLHTE NEEDYDKYGI RIRVKFRSST QLHELTPHHQ SGGERSVSTM LYLMALQELN RCPFRVVDEI NQGMDPINER RVFEMVVNTA CKENTSQYFF ITPKLLQNLP YSEKMTVLFV YNGPHMLEPN TWNLKAFQRR RRRITFTQPS
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 872-1101 of human SMC5 (NP_055925.2).
    Isotype
    IgG
    Top Product
    Discover our top product SMC5 Primary Antibody
  • Application Notes
    WB,1:1000 - 1:3000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))
    Alternative Name
    SMC5 (SMC5 Products)
    Synonyms
    F1N13.60 antibody, F1N13_60 antibody, structural maintenance of chromosomes 5 antibody, SMC-5 antibody, SMC5L1 antibody, MLZ-453 antibody, Smc5l1 antibody, mKIAA0594 antibody, mSMC5 antibody, structural maintenance of chromosomes 5 antibody, structural maintenance of chromosomes 5 S homeolog antibody, SMC5 antibody, smc5 antibody, Smc5 antibody, smc5.S antibody
    Background
    Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres cell lines and mediates sumoylation of shelterin complex (telosome components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression, the function seems to be independent of SMC6. SMC5-SMC6 complex may prevent transcription of episomal DNA, such as circular viral DNA genome.,SMC5,SMC5L1,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,SMC5
    Molecular Weight
    128 kDa
    Gene ID
    23137
    UniProt
    Q8IY18
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