AI987855 antibody, OAT4L antibody, Rst antibody, Slc22al2 antibody, URAT1 antibody, RST antibody, solute carrier family 22 (organic anion/cation transporter), member 12 antibody, solute carrier family 22 member 12 antibody, Slc22a12 antibody, SLC22A12 antibody
Background
The protein encoded by this gene is a member of the organic anion transporter (OAT) family, and it acts as a urate transporter to regulate urate levels in blood. This protein is an integral membrane protein primarily found in epithelial cells of the proximal tubule of the kidney. An elevated level of serum urate, hyperuricemia, is associated with increased incidences of gout, and mutations in this gene cause renal hypouricemia type 1. Alternative splicing results in multiple transcript variants.,SLC22A12,OAT4L,RST,URAT1,SLC22A12