SFRP1 antibody (AA 30-314)

Catalog No. ABIN1682676

Product Details anti-SFRP1 Antibody

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Binding Specificity: AA 30-314

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SFRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SASEYDYVSF QSDIGPYQSG RFYTKPPQCV DIPADLRLCH NVGYKKMVLP NLLEHETMAE VKQQASSWVP LLNKNCHAGT QVFLCSLFAP VCLDRPIYPC RWLCEAVRDS CEPVMQFFGF YWPEMLKCDK FPEGDVCIAM TPPNATEASK PQGTTVCPPC DNELKSEAII EHLCASEFAL RMKIKEVKKE NGDKKIVPKK KKPLKLGPIK KKDLKKLVLY LKNGADCPCH QLDNLSHHFL IMGRKVKSQY LLTAIHKWDK KNKEFKNFMK KMKNHECPTF QSVFK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-314 of human SFRP1 (NP_003003.3).

Isotype: IgG

Application Details

Application Notes: WB,1:100 - 1:500,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SFRP1

Target: SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))

Alternative Name: SFRP1 (SFRP1 Products)

Background: This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.,SFRP1,FRP,FRP-1,FRP1,FrzA,SARP2,Cell Biology & Developmental Biology,Apoptosis,Ubiquitin,Wnt/β-Catenin Signaling Pathway,Neuroscience,Stem Cells,SFRP1

Molecular Weight: 35 kDa

Gene ID: 6422

UniProt: Q8N474

Pathways: WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation