SAP18 antibody (AA 21-172)

Catalog No. ABIN1682621

Product Details anti-SAP18 Antibody

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Binding Specificity: AA 21-172

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAP18 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: AVESRVTQEE IKKEPEKPID REKTCPLLLR VFTTNNGRHH RMDEFSRGNV PSSELQIYTW MDATLKELTS LVKEVYPEAR KKGTHFNFAI VFTDVKRPGY RVKEIGSTMS GRKGTDDSMT LQSQKFQIGD YLDIAITPPN RAPPPSGRMR PY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-172 of human SAP18 (NP_005861.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SAP18

Target: SAP18 (Sin3A-Associated Protein, 18kDa (SAP18))

Alternative Name: SAP18 (SAP18 Products)

Synonyms: zgc:73118 antibody, C530046K05Rik antibody, D11Ertd539e antibody, EMegR4 antibody, Sinbp1 antibody, 2HOR0202 antibody, SAP18P antibody, Sin3A-associated protein antibody, Sin3-associated polypeptide 18 antibody, Sin3A associated protein 18 antibody, Sin3A associated protein 18kDa S homeolog antibody, sap18 antibody, Sap18 antibody, sap18.S antibody, SAP18 antibody

Background: Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.,SAP18,2HOR0202,SAP18P,Epigenetics & Nuclear Signaling,SAP18

Molecular Weight: 17 kDa

Gene ID: 10284

UniProt: O00422