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COMT antibody

COMT Reactivity: Human WB Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7101689
  • Target See all COMT Antibodies
    COMT (Catechol-O-Methyltransferase (COMT))
    Reactivity
    • 54
    • 36
    • 35
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 64
    • 7
    • 3
    • 1
    Rabbit
    Clonality
    • 62
    • 13
    Monoclonal
    Conjugate
    • 43
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This COMT antibody is un-conjugated
    Application
    • 40
    • 23
    • 16
    • 13
    • 13
    • 11
    • 9
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Cross-Reactivity
    Human, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human COMT
    Isotype
    IgG
    Top Product
    Discover our top product COMT Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    COMT (Catechol-O-Methyltransferase (COMT))
    Alternative Name
    COMT (COMT Products)
    Synonyms
    Comt1 antibody, D16Wsu103e antibody, D330014B15Rik antibody, COMT antibody, mb-comt antibody, s-comt antibody, comt antibody, MGC154444 antibody, zgc:114157 antibody, si:dkey-13a21.15 antibody, zK13A21.15 antibody, zgc:162236 antibody, catechol-O-methyltransferase antibody, microRNA 4761 antibody, catechol-O-methyltransferase S homeolog antibody, methyltransferase antibody, catechol-o-methyltransferase antibody, catechol-O-methyltransferase a antibody, catechol-O-methyltransferase b antibody, catechol O-methyltransferase antibody, COMT antibody, Comt antibody, MIR4761 antibody, comt antibody, comt.2 antibody, comt.S antibody, Rv1703c antibody, Mb1729c antibody, comta antibody, comtb antibody, LOC100354142 antibody
    Background
    Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008],HEL-S-98n,Drug metabolism,Endocrine & Metabolism,Epigenetics & Nuclear Signaling,Neurodegenerative Diseases,Neurodegenerative Diseases_Dopamine Signaling in Parkinsons Disease,Neuroscience,Signal Transduction,COMT
    Molecular Weight
    24,28 kDa
    Gene ID
    1312
    UniProt
    P21964
    Pathways
    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
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