PPIF antibody (AA 30-207)

Catalog No. ABIN1682254

Product Details anti-PPIF Antibody

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Binding Specificity: AA 30-207

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIF antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: CSKGSGDPSS SSSSGNPLVY LDVDANGKPL GRVVLELKAD VVPKTAENFR ALCTGEKGFG YKGSTFHRVI PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-207 of human PPIF (NP_005720.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

References for anti-PPIF antibody (ABIN1682254)

Wang, Lin, Chen, Zhu, Jiang, Li, Wang et al.: "Overexpression of mitochondrial Hsp75 protects neural stem cells against microglia-derived soluble factor-induced neurotoxicity by regulating mitochondrial permeability transition pore opening in ..." in: International journal of molecular medicine, Vol. 36, Issue 6, pp. 1487-96, (2016) (PubMed).

Target Details for PPIF

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Alternative Name: PPIF (PPIF Products)

Synonyms: CYP3 antibody, CyP-M antibody, Cyp-D antibody, CypD antibody, CyP-D antibody, ppif antibody, wu:fd61c06 antibody, zgc:101753 antibody, AW457192 antibody, CyP-F antibody, PPIase antibody, Cyp-40 antibody, cypf antibody, peptidylprolyl isomerase F antibody, peptidylprolyl isomerase Fa antibody, peptidylprolyl isomerase F (cyclophilin F) antibody, peptidylprolyl isomerase D antibody, peptidylprolyl isomerase F L homeolog antibody, PPIF antibody, ppifa antibody, Ppif antibody, Ppid antibody, ppif antibody, ppif.L antibody

Background: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.,PPIF,CYP3,CyP-M,Cyp-D,CypD,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,PPIF

Molecular Weight: 16 kDa/22 kDa

Gene ID: 10105

UniProt: P30405

Pathways: Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity