PMM2 antibody (AA 1-246)

Catalog No. ABIN1682208

Product Details anti-PMM2 Antibody

Target: PMM2 (Phosphomannomutase 2 (PMM2))

Binding Specificity: AA 1-246

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMM2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: MAAPGPALCL FDVDGTLTAP RQKITKEMDD FLQKLRQKIK IGVVGGSDFE KVQEQLGNDV VEKYDYVFPE NGLVAYKDGK LLCRQNIQSH LGEALIQDLI NYCLSYIAKI KLPKKRGTFI EFRNGMLNVS PIGRSCSQEE RIEFYELDKK ENIRQKFVAD LRKEFAGKGL TFSIGGQISF DVFPDGWDKR YCLRHVENDG YKTIYFFGDK TMPGGNDHEI FTDPRTMGYS VTAPEDTRRI CELLFS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-246 of human PMM2 (NP_000294.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PMM2

Target: PMM2 (Phosphomannomutase 2 (PMM2))

Alternative Name: PMM2 (PMM2 Products)

Background: The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.,PMM2,CDG1,CDG1a,CDGS,PMI,PMI1,PMM 2,Cancer,Signal Transduction,Endocrine & Metabolism,PMM2

Molecular Weight: 13 kDa/28 kDa

Gene ID: 5373

UniProt: O15305