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PDK2 antibody (AA 128-407)

PDK2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1681304
  • Target See all PDK2 Antibodies
    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
    Binding Specificity
    • 15
    • 10
    • 8
    • 7
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 128-407
    Reactivity
    • 87
    • 53
    • 45
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 80
    • 14
    Rabbit
    Clonality
    • 75
    • 19
    Polyclonal
    Conjugate
    • 41
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDK2 antibody is un-conjugated
    Application
    • 78
    • 49
    • 39
    • 17
    • 14
    • 13
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    PTMAQGVLEY KDTYGDDPVS NQNIQYFLDR FYLSRISIRM LINQHTLIFD GSTNPAHPKH IGSIDPNCNV SEVVKDAYDM AKLLCDKYYM ASPDLEIQEI NAANSKQPIH MVYVPSHLYH MLFELFKNAM RATVESHESS LILPPIKVMV ALGEEDLSIK MSDRGGGVPL RKIERLFSYM YSTAPTPQPG TGGTPLAGFG YGLPISRLYA KYFQGDLQLF SMEGFGTDAV IYLKALSTDS VERLPVYNKS AWRHYQTIQE AGDWCVPSTE PKNTSTYRVS
    Cross-Reactivity
    Human
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 128-407 of human PDK2 (NP_002602.2).
    Isotype
    IgG
    Top Product
    Discover our top product PDK2 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
    Alternative Name
    PDK2 (PDK2 Products)
    Synonyms
    PDHK2 antibody, PDKII antibody, Pdk antibody, zgc:56209 antibody, PDK2 antibody, pyruvate dehydrogenase kinase 2 antibody, pyruvate dehydrogenase kinase, isoenzyme 2 antibody, pyruvate dehydrogenase kinase, isozyme 2b antibody, PDK2 antibody, Pdk2 antibody, pdk2b antibody
    Background
    This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,PDK2,PDHK2,PDKII,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Warburg Effect,PDK2
    Molecular Weight
    38 kDa/46 kDa
    Gene ID
    5164
    UniProt
    Q15119
    Pathways
    PI3K-Akt Signaling, RTK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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