P4HA2 antibody (AA 234-533)

Catalog No. ABIN1681193

Product Details anti-P4HA2 Antibody

Target: P4HA2 (Prolyl 4-Hydroxylase, alpha Polypeptide II (P4HA2))

Binding Specificity: AA 234-533

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P4HA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Sequence: LSLDPSHERA GGNLRYFEQL LEEEREKTLT NQTEAELATP EGIYERPVDY LPERDVYESL CRGEGVKLTP RRQKRLFCRY HHGNRAPQLL IAPFKEEDEW DSPHIVRYYD VMSDEEIERI KEIAKPKLAR ATVRDPKTGV LTVASYRVSK SSWLEEDDDP VVARVNRRMQ HITGLTVKTA ELLQVANYGV GGQYEPHFDF SRRPFDSGLK TEGNRLATFL NYMSDVEAGG ATVFPDLGAA IWPKKGTAVF WYNLLRSGEG DYRTRHAACP VLVGCKWVSN KWFHERGQEF LRPCGSTEVD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 234-533 of human P4HA2 (NP_001136070.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for P4HA2

Target: P4HA2 (Prolyl 4-Hydroxylase, alpha Polypeptide II (P4HA2))

Alternative Name: P4HA2 (P4HA2 Products)

Background: This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.,P4HA2,MYP25,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Endocrine & Metabolism,Amino acid metabolism,P4HA2

Molecular Weight: 60 kDa

Gene ID: 8974

UniProt: O15460