NSUN2 antibody (AA 508-767)

Catalog No. ABIN1681117

Product Details anti-NSUN2 Antibody

Target: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Binding Specificity: AA 508-767

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NSUN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: KKMKLFGFKE DPFVFIPEDD PLFPPIEKFY ALDPSFPRMN LLTRTTEGKK RQLYMVSKEL RNVLLNNSEK MKVINTGIKV WCRNNSGEEF DCAFRLAQEG IYTLYPFINS RIITVSMEDV KILLTQENPF FRKLSSETYS QAKDLAKGSI VLKYEPDSAN PDALQCPIVL CGWRGKASIR TFVPKNERLH YLRMMGLEVL GEKKKEGVIL TNESAASTGQ PDNDVTEGQR AGEPNSPDAE EANSPDVTAG CDPAGVHPPR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 508-767 of human NSUN2 (NP_060225.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for NSUN2

Target: NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))

Alternative Name: NSUN2 (NSUN2 Products)

Background: This gene encodes a methyltransferase that catalyzes the methylation of cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. This modification is necessary to stabilize the anticodon-codon pairing and correctly translate the mRNA. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.,NSUN2,MISU,MRT5,SAKI,TRM4,Epigenetics & Nuclear Signaling,RNA Binding,NSUN2

Molecular Weight: 59 kDa/82 kDa/86 kDa

Gene ID: 54888

UniProt: Q08J23