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RAP1GAP antibody

RAP1GAP Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
Catalog No. ABIN7101534
  • Target See all RAP1GAP Antibodies
    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))
    Reactivity
    • 31
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 22
    • 10
    Rabbit
    Clonality
    • 20
    • 12
    Monoclonal
    Conjugate
    • 18
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RAP1GAP antibody is un-conjugated
    Application
    • 17
    • 9
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Monoclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Rap1GAP
    Isotype
    IgG
    Top Product
    Discover our top product RAP1GAP Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RAP1GAP (RAP1 GTPase Activating Protein (RAP1GAP))
    Alternative Name
    RAP1GAP (RAP1GAP Products)
    Background
    This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011],RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP,Cancer,Epigenetics & Nuclear Signaling,Signal Transduction,Tumor suppressors,RAP1GAP
    Molecular Weight
    95 kDa
    Gene ID
    5909
    UniProt
    P47736
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