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MBD2 antibody (AA 202-411)

MBD2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1680781
  • Target See all MBD2 Antibodies
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Binding Specificity
    • 9
    • 8
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 202-411
    Reactivity
    • 47
    • 23
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 44
    • 2
    • 1
    Rabbit
    Clonality
    • 44
    • 3
    Polyclonal
    Conjugate
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MBD2 antibody is un-conjugated
    Application
    • 40
    • 22
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    DLSSFDFRTG KMMPSKLQKN KQRLRNDPLN QNKGKPDLNT TLPIRQTASI FKQPVTKVTN HPSNKVKSDP QRMNEQPRQL FWEKRLQGLS ASDVTEQIIK TMELPKGLQG VGPGSNDETL LSAVASALHT SSAPITGQVS AAVEKNPAVW LNTSQPLCKA FIVTDEDIRK QEERVQQVRK KLEEALMADI LSRAADTEEM DIEMDSGDEA
    Cross-Reactivity
    Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 202-411 of human MBD2 (NP_003918.1).
    Isotype
    IgG
    Top Product
    Discover our top product MBD2 Primary Antibody
  • Application Notes
    WB,1:200 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
    Alternative Name
    MBD2 (MBD2 Products)
    Synonyms
    MBD2 antibody, DMTase antibody, NY-CO-41 antibody, MBD2a antibody, wu:fa97f06 antibody, zgc:111862 antibody, methyl-CpG binding domain protein 2 antibody, methyl-CpG binding domain protein 2 S homeolog antibody, MBD2 antibody, Mbd2 antibody, mbd2 antibody, mbd2.S antibody
    Background
    DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing. Two transcript variants encoding different isoforms have been found for this gene.,MBD2,DMTase,NY-CO-41,Epigenetics & Nuclear Signaling,MBD2
    Molecular Weight
    31 kDa/43 kDa
    Gene ID
    8932
    UniProt
    Q9UBB5
    Pathways
    Chromatin Binding
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