FOXC1 antibody (AA 404-553)

Catalog No. ABIN1679876

Product Details anti-FOXC1 Antibody

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Binding Specificity: AA 404-553

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AAGERGGHLQ GAPGGAGGSA VDDPLPDYSL PPVTSSSSSS LSHGGGGGGG GGGQEAGHHP AAHQGRLTSW YLNQAGGDLG HLASAAAAAA AAGYPGQQQN FHSVREMFES QRIGLNNSPV NGNSSCQMAF PSSQSLYRTS GAFVYDCSKF

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 404-553 of human FOXC1 (NP_001444.2).

Isotype: IgG

Application Details

Application Notes: WB,1:100 - 1:1000,IHC,1:50 - 1:100

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FOXC1

Target: FOXC1 (Forkhead Box C1 (FOXC1))

Alternative Name: FOXC1 (FOXC1 Products)

Background: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct DNA-binding forkhead domain. The specific function of this gene has not yet been determined, however, it has been shown to play a role in the regulation of embryonic and ocular development. Mutations in this gene cause various glaucoma phenotypes including primary congenital glaucoma, autosomal dominant iridogoniodysgenesis anomaly, and Axenfeld-Rieger anomaly.,FOXC1,ARA,ASGD3,FKHL7,FREAC-3,FREAC3,IGDA,IHG1,IRID1,RIEG3,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,FOXC1

Molecular Weight: 56 kDa

Gene ID: 2296

UniProt: Q12948

Pathways: Chromatin Binding, Glycosaminoglycan Metabolic Process