EXTL3 antibody (AA 52-220)

Catalog No. ABIN1679782

Product Details anti-EXTL3 Antibody

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Binding Specificity: AA 52-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXTL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TTLDEADEAG KRIFGPRVGN ELCEVKHVLD LCRIRESVSE ELLQLEAKRQ ELNSEIAKLN LKIEACKKSI ENAKQDLLQL KNVISQTEHS YKELMAQNQP KLSLPIRLLP EKDDAGLPPP KATRGCRLHN CFDYSRCPLT SGFPVYVYDS DQFVFGSYLD PLVKQAFQA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 52-220 of human EXTL3 (NP_001431.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EXTL3

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Alternative Name: EXTL3 (EXTL3 Products)

Background: This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants.,EXTL3,BOTV,EXTL1L,EXTR1,REGR,RPR,ISDNA,EXTL3

Molecular Weight: 104 kDa

Gene ID: 2137

UniProt: O43909

Pathways: Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling