EXTL3 antibody (AA 52-220)

Catalog No. ABIN1679782

Product Details anti-EXTL3 Antibody

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Binding Specificity: AA 52-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXTL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TTLDEADEAG KRIFGPRVGN ELCEVKHVLD LCRIRESVSE ELLQLEAKRQ ELNSEIAKLN LKIEACKKSI ENAKQDLLQL KNVISQTEHS YKELMAQNQP KLSLPIRLLP EKDDAGLPPP KATRGCRLHN CFDYSRCPLT SGFPVYVYDS DQFVFGSYLD PLVKQAFQA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 52-220 of human EXTL3 (NP_001431.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EXTL3

Target: EXTL3 (Exostoses (Multiple)-Like 3 (EXTL3))

Alternative Name: EXTL3 (EXTL3 Products)

Synonyms: BcDNA:LD21192 antibody, Botv antibody, CG15110 antibody, DEXT3 antibody, DEXTL3 antibody, Dextl3 antibody, Dmel\\CG15110 antibody, Extl3 antibody, 2900009G18Rik antibody, AU040105 antibody, Ext1l antibody, mKIAA0519 antibody, BOTV antibody, EXTL1L antibody, EXTR1 antibody, REGR antibody, RPR antibody, Regr antibody, brother of tout-velu antibody, exostoses (multiple)-like 3 antibody, exostosin like glycosyltransferase 3 antibody, exostosin-like glycosyltransferase 3 antibody, botv antibody, Extl3 antibody, EXTL3 antibody

Background: This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants.,EXTL3,BOTV,EXTL1L,EXTR1,REGR,RPR,ISDNA,EXTL3

Molecular Weight: 104 kDa

Gene ID: 2137

UniProt: O43909

Pathways: Glycosaminoglycan Metabolic Process, ER-Nucleus Signaling