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EPOR antibody (AA 274-508)

Name: EPOR antibody (AA 274-508)
Brand: antibodies-online
SKU: ABIN1679741
Price: 877.74 USD
Availability: InStock

EPOR Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated

Western blot analysis of extracts of various cell lines, using EPOR antibody. (EPOR antibody (AA 274-508))

Immunofluorescence analysis of Mouse fetal using EPOR Rabbit pAb (ABIN3016975, ABIN3016976, ABIN1679740, ABIN1679741 and ABIN6219913) at dilution of 1:100. (EPOR antibody (AA 274-508))

Western blot analysis of extracts of various cell lines, using EPOR antibody (ABIN3016975, ABIN3016976, ABIN1679740, ABIN1679741 and ABIN6219913) at 1:1000 dilution. (EPOR antibody (AA 274-508))

3 images

(1 reference)

Catalog No. ABIN1679741

Datasheet as PDF

Target

EPOR (Erythropoietin Receptor (EPOR))
Binding Specificity
16

11

8

7

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 274-508
Reactivity
109

46

43

9

5

4

3

3

2

2

2

1

1
Human
Host
93

18

5

1
Rabbit
Compatible Secondaries
Clonality
100

16

1
Polyclonal
Conjugate
64

10

7

5

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This EPOR antibody is un-conjugated
Application
86

40

22

21

20

15

14

14

10

5

5

5

4

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF)

Sequence

HRRALKQKIW PGIPSPESEF EGLFTTHKGN FQLWLYQNDG CLWWSPCTPF TEDPPASLEV LSERCWGTMQ AVEPGTDDEG PLLEPVGSEH AQDTYLVLDK WLLPRNPPSE DLPGPGGSVD IVAMDEGSEA SSCSSALASK PSPEGASAAS FEYTILDPSS QLLRPWTLCP ELPPTPPHLK YLYLVVSDSG ISTDYSSGDS QGAQGGLSDG PYSNPYENSL IPAAEPLPPS YVACS

Cross-Reactivity

Human, Mouse, Rat

Characteristics

Polyclonal Antibodies

Purification

Affinity purification

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 274-508 of human EPOR (NP_000112.1).

Isotype

IgG
anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR Reactivity: Human WB, ELISA, IP Host: Mouse Monoclonal 3D10 unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 301-450) antibody
EPOR Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 470-504), (C-Term) antibody
EPOR Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB50846 unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 45-244) antibody
EPOR Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 31-130) antibody
EPOR Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3F6 unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 320-506) antibody
EPOR Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) antibody
EPOR Reactivity: Human FACS, cELISA Host: Mouse Monoclonal VP-2E8 unconjugated

anti-Erythropoietin Receptor (EPOR) (AA 1-508) antibody
EPOR Reactivity: Human WB Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) (pTyr368) antibody
EPOR Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Erythropoietin Receptor (EPOR) (pTyr426) antibody
EPOR Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions

For Research Use only
Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Avoid freeze / thaw cycles.
Kai-lan, Si: "Pretreatment With Erythropoietin Attenuates Intestinal Ischemia Reperfusion Injury by Further Promoting PI3K/Akt Signaling Activation." in: Transplantation proceedings, Vol. 47, Issue 6, pp. 1639-45, (2016) (PubMed).
Target

EPOR (Erythropoietin Receptor (EPOR))

Alternative Name

EPOR

Background

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.,EPOR,EPO-R,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,Stem Cells,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,Heart,Hypertrophy,EPOR

Molecular Weight

26 kDa/35 kDa/55 kDa

Gene ID

2057

UniProt

P19235

Pathways

JAK-STAT Signaling