EDAR antibody (AA 27-187)

Catalog No. ABIN1679644

Product Details anti-EDAR Antibody

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Binding Specificity: AA 27-187

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDAR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: EYSNCGENEY YNQTTGLCQE CPPCGPGEEP YLSCGYGTKD EDYGCVPCPA EKFSKGGYQI CRRHKDCEGF FRATVLTPGD MENDAECGPC LPGYYMLENR PRNIYGMVCY SCLLAPPNTK ECVGATSGAS ANFPGTSGSS TLSPFQHAHK ELSGQGHLAT A

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 27-187 of human EDAR (NP_071731.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for EDAR

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Alternative Name: EDAR (EDAR Products)

Background: This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.,EDAR,DL,ECTD10A,ECTD10B,ED1R,ED3,ED5,EDA-A1R,EDA1R,EDA3,HRM1,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Growth factor,TNF,EDAR

Molecular Weight: 48 kDa/51 kDa

Gene ID: 10913

UniProt: Q9UNE0

Pathways: Tube Formation, Ubiquitin Proteasome Pathway