CYLD antibody (AA 654-953)
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- Target See all CYLD Antibodies
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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Binding Specificity
- AA 654-953
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYLD antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- TKIMKLRKIL EKVEAASGFT SEEKDPEEFL NILFHHILRV EPLLKIRSAG QKVQDCYFYQ IFMEKNEKVG VPTIQQLLEW SFINSNLKFA EAPSCLIIQM PRFGKDFKLF KKIFPSLELN ITDLLEDTPR QCRICGGLAM YECRECYDDP DISAGKIKQF CKTCNTQVHL HPKRLNHKYN PVSLPKDLPD WDWRHGCIPC QNMELFAVLC IETSHYVAFV KYGKDDSAWL FFDSMADRDG GQNGFNIPQV TPCPEVGEYL KMSLEDLHSL DSRRIQGCAR RLLCDAYMCM YQSPTMSLYK
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 654-953 of human CYLD (NP_001035877.1).
- Isotype
- IgG
- Top Product
- Discover our top product CYLD Primary Antibody
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- Application Notes
- WB,1:200 - 1:2000,IHC,1:50 - 1:200
- Restrictions
- For Research Use only
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
- Alternative Name
- CYLD (CYLD Products)
- Background
- This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,CYLD,BRSS,CDMT,CYLD1,CYLDI,EAC,MFT,MFT1,SBS,TEM,USPL2,Epigenetics & Nuclear Signaling,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Ubiquitin,Death Receptor Signaling Pathway,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,CYLD
- Molecular Weight
- 107 kDa
- Gene ID
- 1540
- UniProt
- Q9NQC7
- Pathways
- Apoptosis, Activation of Innate immune Response
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