CLCNKA antibody (AA 470-644)

Catalog No. ABIN1679253

Product Details anti-CLCNKA Antibody

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Binding Specificity: AA 470-644

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCNKA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QSCQPSFYDG TIIVKKLPYL PRILGRNIGS HHVRVEHFMN HSITTLAKDT PLEEVVKVVT STDVTEYPLV ESTESQILVG IVQRAQLVQA LQAEPPSRAP GHQQCLQDIL ARGCPTEPVT LTLFSETTLH QAQNLFKLLN LQSLFVTSRG RAVGCVSWVE MKKAISNLTN PPAPK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 470-644 of human CLCNKA (NP_001244068.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CLCNKA

Target: CLCNKA (Chloride Channel Ka (CLCNKA))

Alternative Name: CLCNKA (CLCNKA Products)

Background: This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.,CLCNKA,CLCK1,ClC-K1,hClC-Ka,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,CLCNKA

Molecular Weight: 70 kDa/75 kDa

Gene ID: 1187

UniProt: P51800

Pathways: Response to Water Deprivation