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Bestrophin 1 antibody (AA 200-300)

BEST1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1678855
  • Target See all Bestrophin 1 (BEST1) Antibodies
    Bestrophin 1 (BEST1)
    Binding Specificity
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-300
    Reactivity
    • 25
    • 5
    • 4
    • 2
    • 2
    • 1
    Human
    Host
    • 21
    • 4
    Rabbit
    Clonality
    • 23
    • 2
    Polyclonal
    Conjugate
    • 16
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Bestrophin 1 antibody is un-conjugated
    Application
    • 16
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RIRDPILLQS LLNEMNTLRT QCGHLYAYDW ISIPLVYTQV VTVAVYSFFL TCLVGRQFLN PAKAYPGHEL DLVVPVFTFL QFFFYVGWLK VAEQLINPFG E
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 200-300 of human BEST1 (NP_004174.1).
    Isotype
    IgG
    Top Product
    Discover our top product BEST1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Bestrophin 1 (BEST1)
    Alternative Name
    BEST1 (BEST1 Products)
    Synonyms
    CG6264 antibody, Dbest antibody, Dmel\\CG6264 antibody, anon-WO0118547.380 antibody, best antibody, dBest1 antibody, dbest1 antibody, dmBest1 antibody, BEST1 antibody, VMD2 antibody, best-1 antibody, ARB antibody, BEST antibody, BMD antibody, RP50 antibody, TU15B antibody, Bmd antibody, Vmd2 antibody, mBest1 antibody, Bestrophin 1 antibody, bestrophin 1 antibody, Best1 antibody, BEST1 antibody, best1 antibody, Bm1_25500 antibody
    Background
    This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.,BEST1,ARB,BEST,BMD,RP50,TU15B,VMD2,Cell Biology & Developmental Biology,Cell Adhesion,Neuroscience,BEST1
    Molecular Weight
    57 kDa/67 kDa/69 kDa
    Gene ID
    7439
    UniProt
    O76090
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