ATG16L1 antibody (AA 90-300)

Catalog No. ABIN1678769

Product Details anti-ATG16L1 Antibody

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Binding Specificity: AA 90-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG16L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: IKHQEELTEL HKKRGELAQL VIDLNNQMQR KDREMQMNEA KIAECLQTIS DLETECLDLR TKLCDLERAN QTLKDEYDAL QITFTALEGK LRKTTEENQE LVTRWMAEKA QEANRLNAEN EKDSRRRQAR LQKELAEAAK EPLPVEQDDD IEVIVDETSD HTEETSPVRA ISRAATKRLS QPAGGLLDSI TNIFGRRSVS SFPVPQDNVD T

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-300 of human ATG16L1 (NP_110430.5).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ATG16L1

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Alternative Name: ATG16L1 (ATG16L1 Products)

Background: The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.,ATG16L1,APG16L,ATG16A,ATG16L,IBD10,WDR30,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Ubiquitin,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,Cardiovascular,Heart,ATGs,ATG16L1

Molecular Weight: 47 kDa/49 kDa/53 kDa/66 kDa/68 kDa

Gene ID: 55054

UniProt: Q676U5

Pathways: Autophagy