Annexin VII antibody (AA 237-466)

Catalog No. ABIN1678673

Product Details anti-Annexin VII Antibody

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Binding Specificity: AA 237-466

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VII antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TYYDAWSLRK AMQGAGTQER VLIEILCTRT NQEIREIVRC YQSEFGRDLE KDIRSDTSGH FERLLVSMCQ GNRDENQSIN HQMAQEDAQR LYQAGEGRLG TDESCFNMIL ATRSFPQLRA TMEAYSRMAN RDLLSSVSRE FSGYVESGLK TILQCALNRP AFFAERLYYA MKGAGTDDST LVRIVVTRSE IDLVQIKQMF AQMYQKTLGT MIAGDTSGDY RRLLLAIVGQ

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 237-466 of human ANXA7 (NP_001147.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Alternative Name: ANXA7 (ANXA7 Products)

Synonyms: ANX7 antibody, SNX antibody, SYNEXIN antibody, AI265384 antibody, AI316497 antibody, Anx7 antibody, synexin antibody, anxa7 antibody, MGC76267 antibody, MGC82023 antibody, ANXA7 antibody, MGC83033 antibody, annexin A7 antibody, annexin VII antibody, annexin A7 S homeolog antibody, ANXA7 antibody, Anxa7 antibody, anxa7 antibody, anxa7.S antibody, PTRG_02166 antibody, BRAFLDRAFT_231082 antibody, PAAG_00136 antibody, MCYG_04180 antibody, VDBG_06328 antibody, MGYG_02426 antibody

Background: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.,ANXA7,ANX7,SNX,SYNEXIN,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Annexins,Cytoskeleton,Neuroscience,Calcium Signaling,ANXA7

Molecular Weight: 50 kDa/52 kDa

Gene ID: 310

UniProt: P20073