ADRM1 antibody (AA 108-407)

Catalog No. ABIN1678593

Product Details anti-ADRM1 Antibody

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Binding Specificity: AA 108-407

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: WMQEPKTDQD EEHCRKVNEY LNNPPMPGAL GASGSSGHEL SALGGEGGLQ SLLGNMSHSQ LMQLIGPAGL GGLGGLGALT GPGLASLLGS SGPPGSSSSS SSRSQSAAVT PSSTTSSTRA TPAPSAPAAA SATSPSPAPS SGNGASTAAS PTQPIQLSDL QSILATMNVP AGPAGGQQVD LASVLTPEIM APILANADVQ ERLLPYLPSG ESLPQTADEI QNTLTSPQFQ QALGMFSAAL ASGQLGPLMC QFGLPAEAVE AANKGDVEAF AKAMQNNAKP EQKEGDTKDK KDEEEDMSLD

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 108-407 of human ADRM1 (NP_008933.2).

Isotype: IgG

Application Details

Application Notes: WB,1:1000 - 1:4000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ADRM1

Target: ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

Alternative Name: ADRM1 (Adrm1 Products)

Background: This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants.,ADRM1,ARM-1,ARM1,GP110,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Cytoskeleton,ADRM1

Molecular Weight: 42 kDa

Gene ID: 11047

UniProt: Q16186

Pathways: Positive Regulation of Endopeptidase Activity