RASSF1 antibody

Catalog No. ABIN165456

Product Details anti-RASSF1 Antibody

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RASSF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogen: Recombinant RASSF1A, Accession / GI number: NP_009113

Clone: 3F3

Isotype: IgG1 kappa

Application Details

Application Notes: Recommended dilution 1:1000(W.B), (ICC)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1mg/ml

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for RASSF1

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Alternative Name: RASSF1A (RASSF1 Products)

Synonyms: RASSF1 antibody, zgc:92505 antibody, wu:fc17f02 antibody, zgc:112224 antibody, 123F2 antibody, NORE2A antibody, RASSF1A antibody, RDA32 antibody, REH3P21 antibody, AA536941 antibody, AU044980 antibody, Rassf1A antibody, Rassf1B antibody, Rassf1C antibody, NPR2-like, GATOR1 complex subunit antibody, Ras association (RalGDS/AF-6) domain family 1 antibody, Ras association domain family member 1 antibody, putative rassf1 antibody, Ras association domain family member 1 L homeolog antibody, Ras association (RalGDS/AF-6) domain family member 1 antibody, NPRL2 antibody, rassf1 antibody, RASSF1 antibody, Smp_157340 antibody, rassf1.L antibody, Rassf1 antibody

Background: The tumor suppressor gene RASSF1A (3p21.3), human Ras association domain family 1A, is expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, small intestine, colon, and peripheral blood leukocytes. RASSF1A expression is inhibited by hypermethylation of the CpG island including the promoter and early transcribed regions of the human RASSF1A gene. Hypermethylated RASSF1A promoter is observed in primary tumors. Furthermore, RASSF1A is related with cell cycle regulation, apoptosis and microtubule stability.