IL-22 antibody

Catalog No. ABIN1607862

Supplier Product No.: 209-401-j33

Product Details anti-IL-22 Antibody

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Supplier Product No.: 209-401-j33

Supplier: Rockland

Purpose: IL-22 Antibody

Cross-Reactivity (Details): This antibody is specific for human IL-22 protein.

Characteristics: Synonyms: rabbit anti-IL-22 antibody, rabbit anti-interleukin-22 antibody, Interleukin22, IL22, ILTIF, ZCYTO18, IL22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor

Purification: Anti-IL-22 is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.

Sterility: Sterile filtered

Immunogen:

Immunogen: Anti-IL-22 antibody was prepared from rabbit antiserum after repeated immunizations with a truncated form of recombinant human IL-22 protein from E. coli.

Immunogen Type: Recombinant Protein

Isotype: IgG

Application Details

Application Notes:

Application Note: IL-22 purified antibody has been tested in western blotting and suitable for ELISA. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 20 kDa in size corresponding to the human IL-22 protein by western blotting in appropriate cell lysate or extract.

Western Blot Dilution: 1:1000-1:2000

ELISA Dilution: 1:20,000 - 1:50,000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for IL-22

Target: IL-22 (IL22) (Interleukin 22 (IL22))

Alternative Name: IL22 (IL22 Products)

Background: Background: Interleukin-22 (IL-22) is a member of a group of cytokines called IL-10 family member, produced by activated dendritic cells and T lymphocytes. IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals via the IL-22R and IL-10Rß receptors to act as a potent mediator of the cellular inflammatory response. Recombinant human IL-22 is a non-disulfide-linked homodimer with a total molecular weight of 33.6 kDa. Anti-IL-22 antibody is ideal for researchers interested in cytokines and stem cell research.

Gene ID: 50616

NCBI Accession: NP_065386

UniProt: Q9GZX6