SYVN1 antibody (Internal Region)

Catalog No. ABIN1590085

Product Details anti-SYVN1 Antibody

Target: SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))

Binding Specificity: Internal Region

Reactivity: Human, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This SYVN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Purpose: SYVN1

Sequence: HERQHLEARL QS

Specificity: This antibody is expected to recognize isoforms a and b (NP_115807.1, NP_757385.1).

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Grade: Verified

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 70 kDa band observed in Human Cerebellum and Rat Lung lysates (calculated MW of 67.6 kDa according to Human NP_115807.1 and 66.9 kDa according to Rat NP_001094209.1). Recommended concentration: 1-3 μg/mL. Primary incubation 1 hour at roo

Peptide ELISA: antibody detection limit dilution 1:32000.

Comment:

Immunofluorescence: Strong expression of the protein seen in the nuclei and endoplasmic reticulum of A431 cells. Recommended concentration: 10μg/ml.

Flow Cytometry: Flow cytometric analysis of A431 cells. Recommended c

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for SYVN1

Target: SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))

Alternative Name: SYVN1 (SYVN1 Products)

Synonyms: DER3 antibody, HRD1 antibody, hrd1 antibody, 1200010C09Rik antibody, AW211966 antibody, C85322 antibody, D530017H19Rik antibody, Hrd1 antibody, RGD1310488 antibody, syvn1 antibody, syvn1-a antibody, syvn1-b antibody, wu:fk91f10 antibody, zgc:55735 antibody, zgc:77108 antibody, synoviolin 1 antibody, synovial apoptosis inhibitor 1, synoviolin antibody, synoviolin 1 S homeolog antibody, SYVN1 antibody, syvn1 antibody, Syvn1 antibody, syvn1.S antibody

Background: SYVN1, synovial apoptosis inhibitor 1, synoviolin, HRD1, KIAA1810, MGC40372, synoviolin 1

Gene ID: 84447, 361712

NCBI Accession: NP_115807, NP_757385

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling