Emilin1 antibody

Catalog No. ABIN1589875

Product Details anti-Emilin1 Antibody

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Emilin1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purpose: Emilin-1 antibody

Specificity: Recombinant mouse Emilin-1

Characteristics: Chromosomal location: 5 B1, 5

Purification: Protein-G purified

Immunogen: Recombinant mouse Emilin-1

Clone: C11A8

Application Details

Application Notes: Western Blot: use at 2-10 μg/mL.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Handling Advice: Centrifuge vial prior to opening.

Storage: 4 °C,-20 °C

Storage Comment: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Expiry Date: 24 months

Target Details for Emilin1

Target: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Alternative Name: Emilin-1 (EMILIN1 Products)

Synonyms: im:7159005 antibody, si:dkey-20n10.2 antibody, wu:fc16f07 antibody, zgc:136949 antibody, EMILIN1 antibody, 5830419M17Rik antibody, AW229038 antibody, BB105748 antibody, EMILIN-1 antibody, gp115 antibody, EMI antibody, EMILIN antibody, elastin microfibril interfacer 1 antibody, elastin microfibril interfacer 1a antibody, elastin microfibril interfacer 1b antibody, elastin microfibril interfacer 1 L homeolog antibody, Emilin1 antibody, emilin1a antibody, emilin1b antibody, EMILIN1 antibody, emilin1.L antibody

Background: Gp115, AW229038, BB105748, EMILIN-1, 5830419M17Rik, elastin microfibril interface located protein 1,Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.

Gene ID: 100952

NCBI Accession: NM_133918, NP_598679

UniProt: Q99K41