DAZL antibody (N-Term)

Catalog No. ABIN1574207

Product Details anti-DAZL Antibody

Target: DAZL (Deleted in Azoospermia-Like (DAZL))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZL antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: DAZL Antibody, pAb, Rabbit detects endogenous levels of mouse and rat DAZL. Predicted to react with human DAZL according to sequence homology.Positive Control: Mouse brain and rat brain

Cross-Reactivity (Details): DAZL Antibody, pAb, Rabbit detects endogenous levels of mouse and rat DAZL. Predicted to react with human DAZL according to sequence homology.Positive Control: Mouse brain and rat brain

Purification: Immunoaffinity chromatography

Immunogen: KLH-coupled synthetic peptide from N-terminal of human DAZL

Isotype: IgG

Application Details

Application Notes: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/mLOther Applications: User optimized

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C/-20 °C

Storage Comment: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Target Details for DAZL

Target: DAZL (Deleted in Azoospermia-Like (DAZL))

Alternative Name: DAZL (DAZL Products)

Synonyms: DAZH antibody, DAZL1 antibody, DAZLA antibody, SPGYLA antibody, DAZL antibody, Xdazl antibody, dazh antibody, dazl1 antibody, dazla antibody, spgyla antibody, dazl-B antibody, dazl-a antibody, Daz-like antibody, Dazh antibody, Dazl1 antibody, Dazla antibody, Tpx-2 antibody, Tpx2 antibody, deleted in azoospermia like antibody, deleted in azoospermia-like antibody, deleted in azoospermia-like L homeolog antibody, DAZL antibody, dazl antibody, Dazl antibody, dazl.L antibody

Background: DAZL is one member of the DAZ family of RNA binding proteins. It plays a role in germ cell development. DAZL is located in the cytoplasm of adult germ cells. Mutations in DAZL have been implicated in severe spermatogenic failure and infertility in males. Expression of DAZL is found in fetal and adult testes and ovaries.DAZL Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human DAZL (Swiss Prot: Q92904).