ENPP1 antibody (C-Term)

Catalog No. ABIN1574138

Product Details anti-ENPP1 Antibody

Target: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Binding Specificity: C-Term

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ENPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: ENPP1 Antibody detects human ENPP1.

Purification: Immunoaffinity chromatography

Immunogen: KLH-coupled synthetic peptide from C-terminal of human ENPP1 .

Isotype: IgG

Application Details

Application Notes: Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/mL.Other Applications: user optimized.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: PBS, pH 7.4, containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Storage: 4 °C/-20 °C

Storage Comment: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Target Details for ENPP1

Target: ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

Alternative Name: ENPP1 (ENPP1 Products)

Synonyms: ENPP1 antibody, si:ch211-142e24.2 antibody, zgc:136238 antibody, ARHR2 antibody, M6S1 antibody, NPP1 antibody, NPPS antibody, PC-1 antibody, PCA1 antibody, PDNP1 antibody, 4833416E15Rik antibody, AI428932 antibody, C76301 antibody, CD203c antibody, E-NPP1 antibody, Ly-41 antibody, Npps antibody, Pca antibody, Pca-1 antibody, Pdnp1 antibody, ttw antibody, twy antibody, Pc1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 1 L homeolog antibody, ENPP1 antibody, enpp1 antibody, enpp1.L antibody, Enpp1 antibody

Background: Ectonucleotide pyrophosphatase 1 (ENPP1) is belongs to a family of nucleotide pyrophosphate phosphodiesterases. It contains a short amino-terminal cytoplasmic tail, a single transmembrane domain, and a large extracellular carboxyl-terminal domain. This cell surface enzyme generates inorganic pyrophosphate which regulates cell differentiation. It serves as a physiological inhibitor of pyrophosphate calcification at least in part by generating ePPi from the dephosphorylation of ATP. Inactivating mutations of ENPP1 are associated with generalized arterial calcification of infancy.
ENPP1 Antibody is developed in goat using a KLH-coupled synthetic peptide from C-terminal of human ENPP1 (Swiss Prot: P22413).

Pathways: Regulation of Carbohydrate Metabolic Process