TFG antibody

Catalog No. ABIN1558081

Product Details anti-TFG Antibody

Target: TFG (Trk-Fused Gene (TFG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TFG antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Specificity: The mouse monoclonal antibody TFG-03 recognizes TFG, an approximately 50 kDa intracellular protein with regulatory functions.

Cross-Reactivity (Details): Human

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Human recombinant protein Trx-his-NTFG

Clone: TFG-03

Isotype: IgG2b

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-5 μg/mL.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for TFG

Target: TFG (Trk-Fused Gene (TFG))

Alternative Name: TFG (TFG Products)

Synonyms: wu:fb11c10 antibody, zgc:55342 antibody, zgc:77230 antibody, HMSNP antibody, SPG57 antibody, TF6 antibody, TRKT3 antibody, AI173908 antibody, trk-fused gene antibody, TRK-fused gene antibody, Trk-fused gene antibody, tfg antibody, TFG antibody, Tfg antibody

Background: Trafficking from ER to golgi regulator,TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.,TF6, TRKT3, SPG57

Gene ID: 10342

UniProt: Q92734