TEK antibody (Extracellular Domain) (Biotin)
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- Target See all TEK Antibodies
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TEK antibody is conjugated to Biotin
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Specificity
- The unconjugated Monoclonal antibody will detect native Human TIE-2/tek in ELISA experiments and on the surface of different Human cell types.
- Purification
- Protein G Chromatography
- Immunogen
- Recombinant Human soluble extracellular domain of TIE-2
- Clone
- Cl-2
- Isotype
- IgG1
- Top Product
- Discover our top product TEK Primary Antibody
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anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 66-185) antibody
TEK Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3A5 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 571-748) antibodyTEK Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 3F5B9 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789) antibodyTEK Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 758-789), (C-Term) antibodyTEK Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB01525-01526 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibodyTEK Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3F8 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 286-465) antibodyTEK Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 401-550) antibodyTEK Reactivity: Human, Mouse, Rat, Cow ELISA, FACS, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (C-Term) antibodyTEK Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 701-800) antibodyTEK Reactivity: Human WB, ELISA Host: Mouse Monoclonal 5G6 unconjugated
anti-TEK Tyrosine Kinase, Endothelial (TEK) (AA 500-750) antibodyTEK Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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FACS analysis and cell sorting: 2-5 μg/mL. ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore to a concentration of 50 μg/mL with sterile PBS solution containing 0.1 % BSA.
- Buffer
- 0.1 M Tris-Cl, 0.1 M NaCl, pH 7.4, 0.02 % Sodium Azide, 50x BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- This product is photosensitive and should be protected from light
- Storage
- 4 °C
- Storage Comment
- Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- Target
- TEK (TEK Tyrosine Kinase, Endothelial (TEK))
- Alternative Name
- CD202b / TEK (TEK Products)
- Background
- TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK
- Gene ID
- 7010
- NCBI Accession
- NP_000450
- UniProt
- Q02763
- Pathways
- RTK Signaling, Growth Factor Binding
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