TP53INP1 antibody (N-Term)

Catalog No. ABIN155075

Product Details anti-TP53INP1 Antibody

Target: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53INP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: The antibody detects the 27 kDa p53DINP1-alpha. A lower band (~18 kDa) which represents the p53DINP1-beta was also detected in certain tissue and cells.

Purification: Affinity Chromatography.

Immunogen: Synthetic peptide mapping to the N-terminus of Human p53DINP1.

Application Details

Application Notes: Western Blot: 0.5-4.0 μg/mL. Immunohistochemistry: 5-10 μg/mL. Human Lung tissue lysate can be used as a Positive Control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or (in aliquots) at -70 °C for long term storage.

Target Details for TP53INP1

Target: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Alternative Name: TP53INP1 (TP53INP1 Products)

Background: P53DINP1 (p53-dependent damage-inducible nuclear protein 1) encodes two proteins termed p53DINP1-alpha (27 kDa) and p53DINP1-beta (18 kDa). p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. p53DINP1 is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.Synonyms: P53DINP1, SIP, Stress-induced protein, Tumor protein p53-inducible nuclear protein 1, p53-dependent damage-inducible nuclear protein 1, p53-inducible nuclear protein 1

Gene ID: 94241

NCBI Accession: NP_001129205

UniProt: Q96A56