PODXL antibody (C-Term)

Catalog No. ABIN1540003

Product Details anti-PODXL Antibody

Target: PODXL (Podocalyxin-Like (PODXL))

Binding Specificity: AA 410-439, C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PODXL antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This PODXL antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the C-terminal region of human PODXL.

Clone: 632CT5-11-4

Isotype: IgG1

Application Details

Application Notes: IF: 1:100. WB: 1:16000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: PODXL Antibody (C-term)(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-PODXL antibody (ABIN1540003)

San, Prost, Williams, Moss, Nuber: "High Podocalyxin levels promote cell viability partially through up-regulation of Annexin A2." in: Biochemical and biophysical research communications, Vol. 478, Issue 2, pp. 573-9, (2016) (PubMed).

Target Details for PODXL

Target: PODXL (Podocalyxin-Like (PODXL))

Alternative Name: PODXL (PODXL Products)

Background: This gene encodes a member of the sialomucin protein family. The encoded protein was originally identified as an important component of glomerular podocytes. Podocytes are highly differentiated epithelial cells with interdigitating foot processes covering the outer aspect of the glomerular basement membrane. Other biological activities of the encoded protein include: binding in a membrane protein complex with Na+/H+ exchanger regulatory factor to intracellular cytoskeletal elements, playing a role in hematopoetic cell differentiation, and being expressed in vascular endothelium cells and binding to L-selectin.

Molecular Weight: 58635

Gene ID: 5420

NCBI Accession: NP_001018121, NP_005388

UniProt: O00592

Pathways: Tube Formation