CDKN1C antibody (AA 34-64)

Catalog No. ABIN1539929

Product Details anti-CDKN1C Antibody

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Binding Specificity: AA 34-64

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDKN1C antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This CDKN1C antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 34-64 amino acids from human CDKN1C.

Clone: 522CT9-5-1

Isotype: IgM

Application Details

Application Notes: WB: 1:500~16000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CDKN1C Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

Target Details for CDKN1C

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Alternative Name: CDKN1C (CDKN1C Products)

Synonyms: BWCR antibody, BWS antibody, KIP2 antibody, WBS antibody, p57 antibody, p57Kip2 antibody, cb961 antibody, p27Xic1-a antibody, zgc:86618 antibody, AL024410 antibody, CDKI antibody, Kip2 antibody, p57(kip2) antibody, p57KIP2 antibody, cyclin dependent kinase inhibitor 1C antibody, cyclin-dependent kinase inhibitor 1Ca antibody, cyclin-dependent kinase inhibitor 1C (P57) antibody, cyclin-dependent kinase inhibitor 1C antibody, CDKN1C antibody, cdkn1ca antibody, Cdkn1c antibody

Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight: 32177

Gene ID: 1028

NCBI Accession: NP_000067, NP_001116102, NP_001116103

UniProt: P49918

Pathways: Cell Division Cycle, Dopaminergic Neurogenesis