MX1 antibody (AA 617-646)

Catalog No. ABIN1539914

Product Details anti-MX1 Antibody

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Binding Specificity: AA 617-646

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MX1 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pig

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This MX1 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 617-646 amino acids from human MX1.

Clone: 474CT4-1-5

Isotype: IgG2b

Application Details

Application Notes: WB: 1:100~500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MX1 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Expiry Date: 6 months

References for anti-MX1 antibody (ABIN1539914)

Voigt, Yin: "Kinetic Differences and Synergistic Antiviral Effects Between Type I and Type III Interferon Signaling Indicate Pathway Independence." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, (2015) (PubMed).

Swick, Baltes, Yin: "Visualizing infection spread: dual-color fluorescent reporting of virus-host interactions." in: Biotechnology and bioengineering, Vol. 111, Issue 6, pp. 1200-9, (2014) (PubMed).

Target Details for MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Alternative Name: MX1 (MX1 Products)

Synonyms: IFI78 antibody, AI893580 antibody, Mx antibody, Mx-1 antibody, IFI-78K antibody, MX antibody, MxA antibody, Mx1-b antibody, Mx1B antibody, OGTPBP antibody, ONBP antibody, myxovirus (influenza virus) resistance 1 antibody, MX dynamin-like GTPase 1 antibody, MX dynamin like GTPase 1 antibody, Mx1 antibody, MX1 antibody

Background: In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 75520

Gene ID: 4599

NCBI Accession: NP_001138397, NP_001171517, NP_002453

UniProt: P20591