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Tuberin antibody
TSC2
Reactivity: Mouse
WB, IF
Host: Mouse
Monoclonal
249CT19-1-3
unconjugated
Product Details anti-Tuberin Antibody
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Target
See all Tuberin (TSC2) Antibodies
Tuberin (TSC2)
(Tuberous Sclerosis 2 (TSC2))
Reactivity
All reactivities for Tuberin antibodies
Mouse
Host
All hosts for Tuberin antibodies
Mouse
Clonality
All clonalities for Tuberin antibodies
Monoclonal
Conjugate
All conjugates for Tuberin antibodies
This Tuberin antibody is un-conjugated
Application
All applications for Tuberin antibodies
Western Blotting (WB), Immunofluorescence (IF)
Purification
This antibody is purified through a protein G column, followed by dialysis against PBS.
Immunogen
This TSC2 monoclonal antibody is generated from mouse immunized with TSC2 recombinant protein.
Clone
249CT19-1-3
Isotype
IgG1 kappa
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Alternatives
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Application Details
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Application Notes
IF: 1:10~50. WB: 1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
TSC2 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for Tuberin
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Target
Tuberin (TSC2)
(Tuberous Sclerosis 2 (TSC2))
Alternative Name
TSC2 (TSC2 Products )
Synonyms
TSC2 antibody, fc16b02 antibody, tuberin antibody, wu:fc16b02 antibody, LAM antibody, TSC4 antibody, Nafld antibody, Tcs2 antibody, Rc antibody, TSC complex subunit 2 antibody, tuberin antibody, hypothetical protein antibody, tuberous sclerosis 2 antibody, TSC2 antibody, LOC5569538 antibody, tsc2 antibody, PGTG_00159 antibody, Tsc2 antibody
Background
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Molecular Weight
200608
Gene ID
7249
NCBI Accession
NP_000539 , NP_001070651 , NP_001107854
UniProt
P49815
Pathways
RTK Signaling , AMPK Signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Regulation of Cell Size , Tube Formation , Protein targeting to Nucleus
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