TOPBP1 antibody (pSer1138)

Catalog No. ABIN1539688

Product Details anti-TOPBP1 Antibody

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Binding Specificity: pSer1138

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TOPBP1 antibody is un-conjugated

Application: Dot Blot (DB)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TOPBP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1138 of human TOPBP1.

Clone: RB36322

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Phospho-TOPBP1-S1138 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the Phospho-TOPBP1-S1138 Antibody at -20 °C.

Expiry Date: 6 months

Target Details for TOPBP1

Target: TOPBP1 (Topoisomerase (DNA) II Binding Protein 1 (TOPBP1))

Alternative Name: TOPBP1 (TOPBP1 Products)

Background: This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands.

Molecular Weight: 170679

Gene ID: 11073

NCBI Accession: NP_008958

UniProt: Q92547

Pathways: Chromatin Binding